8020-5184 Screening compound: 2-(morpholin-4-yl)-5-(thiophen-3-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one

8020-5184 Screening compound: 2-(morpholin-4-yl)-5-(thiophen-3-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one
8020-5184 Screening compound: 2-(morpholin-4-yl)-5-(thiophen-3-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8020-5184
2-(morpholin-4-yl)-5-(thiophen-3-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8020-5184

Molecular Formula

C15H14N4O2S (C15 H14 N4 O2 S)

Compound Name

2-(morpholin-4-yl)-5-(thiophen-3-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one

IUPAC name

2-(morpholin-4-yl)-5-(thiophen-3-yl)-3H4H-pyrido[23-d]pyrimidin-4-one

SMILES

O=C1NC(N2CCOCC2)=Nc2nccc(-c3cscc3)c12

InChI

InChI=1S/C15H14N4O2S/c20-14-12-11(10-2-8-22-9-10)1-3-16-13(12)17-15(18-14)19-4-6-21-7-5-19/h1-3,8-9H,4-7H2,(H,16,17,18,20)

InChI Key

SYEWRWTVMLLXKN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18204540

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

314.37

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.787

Distribution Coefficient, logD

1.783

Water Solubility, LogSw

-2.64

Polar Surface Area

56.236

Acid Dissociation Constant (pKa)

9.41

Base Dissociation Constant (pKb)

4.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

8020-5184 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8020-5184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8020-5184?
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What is the minimum amount of 8020-5184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8020-5184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8020-5184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8020-5184 available by request