8173-0150 Screening compound: 5-tert-butyl-3-(3-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

8173-0150 Screening compound: 5-tert-butyl-3-(3-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
8173-0150 Screening compound: 5-tert-butyl-3-(3-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8173-0150
5-tert-butyl-3-(3-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8173-0150

Molecular Formula

C17H15ClF3N3 (C17 H15 ClF3 N3)

Compound Name

5-tert-butyl-3-(3-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

IUPAC name

5-tert-butyl-3-(3-chlorophenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine

SMILES

CC(C)(C)c(cc(C(F)(F)F)n1nc2)nc1c2-c1cccc(Cl)c1

InChI

InChI=1S/C17H15ClF3N3/c1-16(2,3)13-8-14(17(19,20)21)24-15(23-13)12(9-22-24)10-5-4-6-11(18)7-10/h4-9H,1-3H3

InChI Key

CNZIOJYIKSOJSR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08575751

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.77

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.812

Distribution Coefficient, logD

5.812

Water Solubility, LogSw

-6.22

Polar Surface Area

19.168

Acid Dissociation Constant (pKa)

30.41

Base Dissociation Constant (pKb)

3.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

8173-0150 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 8173-0150 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8173-0150?
Check Price and Availability of 8173-0150, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8173-0150 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8173-0150
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8173-0150
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8173-0150 available by request