8188-1277 Screening compound: 5-(4-bromophenyl)-N-[5-(furan-2-amido)-2-methoxyphenyl]furan-2-carboxamide

8188-1277 Screening compound: 5-(4-bromophenyl)-N-[5-(furan-2-amido)-2-methoxyphenyl]furan-2-carboxamide
8188-1277 Screening compound: 5-(4-bromophenyl)-N-[5-(furan-2-amido)-2-methoxyphenyl]furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8188-1277
5-(4-bromophenyl)-N-[5-(furan-2-amido)-2-methoxyphenyl]furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8188-1277

Molecular Formula

C23H17BrN2O5 (C23 H17 BrN2 O5)

Compound Name

5-(4-bromophenyl)-N-[5-(furan-2-amido)-2-methoxyphenyl]furan-2-carboxamide

IUPAC name

5-(4-bromophenyl)-N-[5-(furan-2-amido)-2-methoxyphenyl]furan-2-carboxamide

SMILES

COc(ccc(NC(c1ccco1)=O)c1)c1NC(c1ccc(-c(cc2)ccc2Br)o1)=O

InChI

InChI=1S/C23H17BrN2O5/c1-29-19-9-8-16(25-22(27)20-3-2-12-30-20)13-17(19)26-23(28)21-11-10-18(31-21)14-4-6-15(24)7-5-14/h2-13H,1H3,(H,25,27)(H,26,28)

InChI Key

VYIAITKLJZQXPP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04380534

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.3

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.206

Distribution Coefficient, logD

5.206

Water Solubility, LogSw

-5.17

Polar Surface Area

70.331

Acid Dissociation Constant (pKa)

10.74

Base Dissociation Constant (pKb)

2.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

8188-1277 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with 8188-1277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8188-1277?
Check Price and Availability of 8188-1277, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8188-1277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8188-1277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8188-1277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8188-1277 available by request