8228-4174 Screening compound: 5-[(3-bromophenyl)[(pyridin-2-yl)amino]methyl]quinolin-6-ol

8228-4174 Screening compound: 5-[(3-bromophenyl)[(pyridin-2-yl)amino]methyl]quinolin-6-ol
8228-4174 Screening compound: 5-[(3-bromophenyl)[(pyridin-2-yl)amino]methyl]quinolin-6-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound 8228-4174
5-[(3-bromophenyl)[(pyridin-2-yl)amino]methyl]quinolin-6-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8228-4174

Molecular Formula

C21H16BrN3O (C21 H16 BrN3 O)

Compound Name

5-[(3-bromophenyl)[(pyridin-2-yl)amino]methyl]quinolin-6-ol

IUPAC name

5-[(3-bromophenyl)[(pyridin-2-yl)amino]methyl]quinolin-6-ol

SMILES

Oc1c(C(c2cccc(Br)c2)Nc2ncccc2)c2cccnc2cc1

InChI

InChI=1S/C21H16BrN3O/c22-15-6-3-5-14(13-15)21(25-19-8-1-2-11-24-19)20-16-7-4-12-23-17(16)9-10-18(20)26/h1-13,21,26H,(H,24,25)/t21-/m0/s1

InChI Key

IOJCTGUDFQVUEZ-NRFANRHFSA-N

MDL Number (MFCD)

MFCD13967360

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.28

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.043

Distribution Coefficient, logD

5.032

Water Solubility, LogSw

-4.74

Polar Surface Area

44.479

Acid Dissociation Constant (pKa)

9.84

Base Dissociation Constant (pKb)

5.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

4.80

8228-4174 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

DGK Inhibitors Library (10558 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 8228-4174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8228-4174?
Check Price and Availability of 8228-4174, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8228-4174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8228-4174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8228-4174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8228-4174 available by request