8290-03378 Screening compound: (2E)-3-(4-chlorophenyl)-N-[2-methyl-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]prop-2-enamide

8290-03378 Screening compound: (2E)-3-(4-chlorophenyl)-N-[2-methyl-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]prop-2-enamide
8290-03378 Screening compound: (2E)-3-(4-chlorophenyl)-N-[2-methyl-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8290-03378
(2E)-3-(4-chlorophenyl)-N-[2-methyl-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8290-03378

Molecular Formula

C24H19ClN2O2 (C24 H19 ClN2 O2)

Compound Name

(2E)-3-(4-chlorophenyl)-N-[2-methyl-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]prop-2-enamide

IUPAC name

(2E)-3-(4-chlorophenyl)-N-[2-methyl-5-(5-methyl-13-benzoxazol-2-yl)phenyl]prop-2-enamide

SMILES

Cc(cc1)cc2c1oc(-c1cc(NC(/C=C/c(cc3)ccc3Cl)=O)c(C)cc1)n2

InChI

InChI=1S/C24H19ClN2O2/c1-15-3-11-22-21(13-15)27-24(29-22)18-8-4-16(2)20(14-18)26-23(28)12-7-17-5-9-19(25)10-6-17/h3-14H,1-2H3,(H,26,28)

InChI Key

KRPPTGATVABOBZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08677821

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.88

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.349

Distribution Coefficient, logD

6.349

Water Solubility, LogSw

-6.41

Polar Surface Area

39.229

Acid Dissociation Constant (pKa)

13.09

Base Dissociation Constant (pKb)

3.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

8290-03378 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

KRAS-Targeted Library (16000 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8290-03378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8290-03378?
Check Price and Availability of 8290-03378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8290-03378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8290-03378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8290-03378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8290-03378 available by request