8293-0176 Screening compound: 2-(2-oxo-3,4-dihydro-2H-1-benzopyran-4-yl)-N-(1,3-thiazol-2-yl)acetamide

8293-0176 Screening compound: 2-(2-oxo-3,4-dihydro-2H-1-benzopyran-4-yl)-N-(1,3-thiazol-2-yl)acetamide
8293-0176 Screening compound: 2-(2-oxo-3,4-dihydro-2H-1-benzopyran-4-yl)-N-(1,3-thiazol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8293-0176
2-(2-oxo-3,4-dihydro-2H-1-benzopyran-4-yl)-N-(1,3-thiazol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8293-0176

Molecular Formula

C14H12N2O3S (C14 H12 N2 O3 S)

Compound Name

2-(2-oxo-3,4-dihydro-2H-1-benzopyran-4-yl)-N-(1,3-thiazol-2-yl)acetamide

IUPAC name

2-(2-oxo-34-dihydro-2H-1-benzopyran-4-yl)-N-(13-thiazol-2-yl)acetamide

SMILES

O=C(CC(C1)c(cccc2)c2OC1=O)Nc1nccs1

InChI

InChI=1S/C14H12N2O3S/c17-12(16-14-15-5-6-20-14)7-9-8-13(18)19-11-4-2-1-3-10(9)11/h1-6,9H,7-8H2,(H,15,16,17)/t9-/m0/s1

InChI Key

GIQYQFSLDKGVLY-VIFPVBQESA-N

MDL Number (MFCD)

MFCD06621783

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

288.33

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.106

Distribution Coefficient, logD

2.102

Water Solubility, LogSw

-2.88

Polar Surface Area

54.002

Acid Dissociation Constant (pKa)

9.44

Base Dissociation Constant (pKb)

1.17

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.40

8293-0176 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Nuclear receptors
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 8293-0176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8293-0176?
Check Price and Availability of 8293-0176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8293-0176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8293-0176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8293-0176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8293-0176 available by request