8323-0271 Screening compound: 3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methylphenyl)-1-(4-methoxyphenyl)urea

8323-0271 Screening compound: 3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methylphenyl)-1-(4-methoxyphenyl)urea
8323-0271 Screening compound: 3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methylphenyl)-1-(4-methoxyphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound 8323-0271
3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methylphenyl)-1-(4-methoxyphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8323-0271

Molecular Formula

C21H19N5O2 (C21 H19 N5 O2)

Compound Name

3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methylphenyl)-1-(4-methoxyphenyl)urea

IUPAC name

3-(5-{imidazo[12-a]pyrimidin-2-yl}-2-methylphenyl)-1-(4-methoxyphenyl)urea

SMILES

Cc(ccc(-c1cn(cccn2)c2n1)c1)c1NC(Nc(cc1)ccc1OC)=O

InChI

InChI=1S/C21H19N5O2/c1-14-4-5-15(19-13-26-11-3-10-22-20(26)24-19)12-18(14)25-21(27)23-16-6-8-17(28-2)9-7-16/h3-13H,1-2H3,(H2,23,25,27)

InChI Key

DJHGVDZOVJEPRE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06433579

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.490

Distribution Coefficient, logD

3.489

Water Solubility, LogSw

-3.64

Polar Surface Area

59.259

Acid Dissociation Constant (pKa)

12.85

Base Dissociation Constant (pKb)

4.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

8323-0271 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 8323-0271 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8323-0271?
Check Price and Availability of 8323-0271, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8323-0271 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8323-0271
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8323-0271
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8323-0271 available by request