8343-0164 Screening compound: N-[7-(3-chlorophenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]furan-2-carboxamide

8343-0164 Screening compound: N-[7-(3-chlorophenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]furan-2-carboxamide
8343-0164 Screening compound: N-[7-(3-chlorophenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8343-0164
N-[7-(3-chlorophenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8343-0164

Molecular Formula

C19H14ClN3O3 (C19 H14 ClN3 O3)

Compound Name

N-[7-(3-chlorophenyl)-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl]furan-2-carboxamide

IUPAC name

N-[7-(3-chlorophenyl)-5-oxo-5678-tetrahydroquinazolin-2-yl]furan-2-carboxamide

SMILES

O=C(c1ccco1)Nc(nc1)nc(CC(C2)c3cccc(Cl)c3)c1C2=O

InChI

InChI=1S/C19H14ClN3O3/c20-13-4-1-3-11(7-13)12-8-15-14(16(24)9-12)10-21-19(22-15)23-18(25)17-5-2-6-26-17/h1-7,10,12H,8-9H2,(H,21,22,23,25)/t12-/m0/s1

InChI Key

FNOKSIVFDDZVMD-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD04166242

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.79

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.307

Distribution Coefficient, logD

2.640

Water Solubility, LogSw

-3.67

Polar Surface Area

66.533

Acid Dissociation Constant (pKa)

6.84

Base Dissociation Constant (pKb)

-2.76

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.80

8343-0164 in Drug Discovery

Included in Screening Libraries

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8343-0164 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8343-0164?
Check Price and Availability of 8343-0164, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8343-0164 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8343-0164
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8343-0164
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8343-0164 available by request