8343-0168 Screening compound: 7-(4-fluorophenyl)-2-[(4-methoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

8343-0168 Screening compound: 7-(4-fluorophenyl)-2-[(4-methoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one
8343-0168 Screening compound: 7-(4-fluorophenyl)-2-[(4-methoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8343-0168
7-(4-fluorophenyl)-2-[(4-methoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8343-0168

Molecular Formula

C21H18FN3O2 (C21 H18 FN3 O2)

Compound Name

7-(4-fluorophenyl)-2-[(4-methoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

IUPAC name

7-(4-fluorophenyl)-2-[(4-methoxyphenyl)amino]-5678-tetrahydroquinazolin-5-one

SMILES

COc(cc1)ccc1Nc(nc1)nc(CC(C2)c(cc3)ccc3F)c1C2=O

InChI

InChI=1S/C21H18FN3O2/c1-27-17-8-6-16(7-9-17)24-21-23-12-18-19(25-21)10-14(11-20(18)26)13-2-4-15(22)5-3-13/h2-9,12,14H,10-11H2,1H3,(H,23,24,25)/t14-/m0/s1

InChI Key

YCKMSMCEBUZODX-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD05695176

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

363.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.332

Distribution Coefficient, logD

4.332

Water Solubility, LogSw

-4.35

Polar Surface Area

51.319

Acid Dissociation Constant (pKa)

16.49

Base Dissociation Constant (pKb)

0.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.00

8343-0168 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8343-0168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8343-0168?
Check Price and Availability of 8343-0168, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8343-0168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8343-0168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8343-0168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8343-0168 available by request