8343-0187 Screening compound: 7-(furan-2-yl)-2-[(4-phenoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

8343-0187 Screening compound: 7-(furan-2-yl)-2-[(4-phenoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one
8343-0187 Screening compound: 7-(furan-2-yl)-2-[(4-phenoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8343-0187
7-(furan-2-yl)-2-[(4-phenoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8343-0187

Molecular Formula

C24H19N3O3 (C24 H19 N3 O3)

Compound Name

7-(furan-2-yl)-2-[(4-phenoxyphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

IUPAC name

7-(furan-2-yl)-2-[(4-phenoxyphenyl)amino]-5678-tetrahydroquinazolin-5-one

SMILES

O=C(CC(C1)c2ccco2)c2c1nc(Nc(cc1)ccc1Oc1ccccc1)nc2

InChI

InChI=1S/C24H19N3O3/c28-22-14-16(23-7-4-12-29-23)13-21-20(22)15-25-24(27-21)26-17-8-10-19(11-9-17)30-18-5-2-1-3-6-18/h1-12,15-16H,13-14H2,(H,25,26,27)/t16-/m1/s1

InChI Key

QEEIRJPEZQFCQY-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD05699628

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.129

Distribution Coefficient, logD

5.129

Water Solubility, LogSw

-5.10

Polar Surface Area

59.102

Acid Dissociation Constant (pKa)

16.67

Base Dissociation Constant (pKb)

0.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

8343-0187 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8343-0187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8343-0187?
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What is the minimum amount of 8343-0187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8343-0187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8343-0187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8343-0187 available by request