8397-0127 Screening compound: 7-{[(2-chlorophenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol

8397-0127 Screening compound: 7-{[(2-chlorophenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol
8397-0127 Screening compound: 7-{[(2-chlorophenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound 8397-0127
7-{[(2-chlorophenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8397-0127

Molecular Formula

C21H16ClN3O (C21 H16 ClN3 O)

Compound Name

7-{[(2-chlorophenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol

IUPAC name

7-{[(2-chlorophenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol

SMILES

Oc1c(C(c2cnccc2)Nc(cccc2)c2Cl)ccc2cccnc12

InChI

InChI=1S/C21H16ClN3O/c22-17-7-1-2-8-18(17)25-19(15-6-3-11-23-13-15)16-10-9-14-5-4-12-24-20(14)21(16)26/h1-13,19,25-26H/t19-/m0/s1

InChI Key

DVBWOZORMNVQDE-IBGZPJMESA-N

MDL Number (MFCD)

MFCD08823463

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.83

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.333

Distribution Coefficient, logD

4.325

Water Solubility, LogSw

-4.20

Polar Surface Area

43.386

Acid Dissociation Constant (pKa)

10.20

Base Dissociation Constant (pKb)

5.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

4.80

8397-0127 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anti-infective Library (19449 compounds)

Antiviral Library (67538 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Targeted Diversity Library (40567 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
Targets:
  • Proteases
  • Others

References: we are preparing a list of scientific research reports with 8397-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8397-0127?
Check Price and Availability of 8397-0127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8397-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8397-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8397-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8397-0127 available by request