8397-0573 Screening compound: 7-{[(4-chloro-2-methylphenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol

8397-0573 Screening compound: 7-{[(4-chloro-2-methylphenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol
8397-0573 Screening compound: 7-{[(4-chloro-2-methylphenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound 8397-0573
7-{[(4-chloro-2-methylphenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8397-0573

Molecular Formula

C22H18ClN3O (C22 H18 ClN3 O)

Compound Name

7-{[(4-chloro-2-methylphenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol

IUPAC name

7-{[(4-chloro-2-methylphenyl)amino](pyridin-3-yl)methyl}quinolin-8-ol

SMILES

Cc(cc(cc1)Cl)c1NC(c1cnccc1)c(ccc1cccnc11)c1O

InChI

InChI=1S/C22H18ClN3O/c1-14-12-17(23)7-9-19(14)26-20(16-5-2-10-24-13-16)18-8-6-15-4-3-11-25-21(15)22(18)27/h2-13,20,26-27H,1H3/t20-/m0/s1

InChI Key

XFPJCYOPVIHOJB-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD08823890

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.86

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.150

Distribution Coefficient, logD

5.142

Water Solubility, LogSw

-5.38

Polar Surface Area

43.386

Acid Dissociation Constant (pKa)

10.20

Base Dissociation Constant (pKb)

5.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

9.10

8397-0573 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antiviral Library (67538 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

DGK Inhibitors Library (10558 compounds)

Targeted Diversity Library (40567 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with 8397-0573 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8397-0573?
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What is the minimum amount of 8397-0573 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8397-0573
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8397-0573
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8397-0573 available by request