8399-0928 Screening compound: 8-(4-chlorophenyl)-2-phenyl-1H,2H,3H,6H,7H,8H,9H-pyrazolo[3,4-c]isoquinoline-1,6-dione

8399-0928 Screening compound: 8-(4-chlorophenyl)-2-phenyl-1H,2H,3H,6H,7H,8H,9H-pyrazolo[3,4-c]isoquinoline-1,6-dione
8399-0928 Screening compound: 8-(4-chlorophenyl)-2-phenyl-1H,2H,3H,6H,7H,8H,9H-pyrazolo[3,4-c]isoquinoline-1,6-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 8399-0928
8-(4-chlorophenyl)-2-phenyl-1H,2H,3H,6H,7H,8H,9H-pyrazolo[3,4-c]isoquinoline-1,6-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8399-0928

Molecular Formula

C22H16ClN3O2 (C22 H16 ClN3 O2)

Compound Name

8-(4-chlorophenyl)-2-phenyl-1H,2H,3H,6H,7H,8H,9H-pyrazolo[3,4-c]isoquinoline-1,6-dione

IUPAC name

8-(4-chlorophenyl)-2-phenyl-1H2H3H6H7H8H9H-pyrazolo[34-c]isoquinoline-16-dione

SMILES

O=C1N(c2ccccc2)Nc(nc2)c1c(CC(C1)c(cc3)ccc3Cl)c2C1=O

InChI

InChI=1S/C22H16ClN3O2/c23-15-8-6-13(7-9-15)14-10-17-18(19(27)11-14)12-24-21-20(17)22(28)26(25-21)16-4-2-1-3-5-16/h1-9,12,14H,10-11H2,(H,24,25)/t14-/m0/s1

InChI Key

JYEZHMMVBFOZEN-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD07181708

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.84

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.176

Distribution Coefficient, logD

4.176

Water Solubility, LogSw

-5.08

Polar Surface Area

51.848

Acid Dissociation Constant (pKa)

11.36

Base Dissociation Constant (pKb)

-2.81

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.60

8399-0928 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 8399-0928 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8399-0928?
Check Price and Availability of 8399-0928, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8399-0928 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8399-0928
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8399-0928
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8399-0928 available by request