8436-0208 Screening compound: 2-(2,4-dimethoxyphenyl)-5-{[(4-iodophenyl)methyl]sulfanyl}-1,3,4-oxadiazole

8436-0208 Screening compound: 2-(2,4-dimethoxyphenyl)-5-{[(4-iodophenyl)methyl]sulfanyl}-1,3,4-oxadiazole
8436-0208 Screening compound: 2-(2,4-dimethoxyphenyl)-5-{[(4-iodophenyl)methyl]sulfanyl}-1,3,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 8436-0208
2-(2,4-dimethoxyphenyl)-5-{[(4-iodophenyl)methyl]sulfanyl}-1,3,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8436-0208

Molecular Formula

C17H15IN2O3S (C17 H15 IN2 O3 S)

Compound Name

2-(2,4-dimethoxyphenyl)-5-{[(4-iodophenyl)methyl]sulfanyl}-1,3,4-oxadiazole

IUPAC name

2-(24-dimethoxyphenyl)-5-{[(4-iodophenyl)methyl]sulfanyl}-134-oxadiazole

SMILES

COc(cc1)cc(OC)c1-c(o1)nnc1SCc(cc1)ccc1I

InChI

InChI=1S/C17H15IN2O3S/c1-21-13-7-8-14(15(9-13)22-2)16-19-20-17(23-16)24-10-11-3-5-12(18)6-4-11/h3-9H,10H2,1-2H3

InChI Key

RKUXMJFXZNKRSM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10465627

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.29

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.451

Distribution Coefficient, logD

4.451

Water Solubility, LogSw

-4.44

Polar Surface Area

45.238

Acid Dissociation Constant (pKa)

24.21

Base Dissociation Constant (pKb)

-1.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

8436-0208 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8436-0208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8436-0208?
Check Price and Availability of 8436-0208, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8436-0208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8436-0208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8436-0208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8436-0208 available by request