8436-0280 Screening compound: 2-(2,4-dimethoxyphenyl)-5-(methylsulfanyl)-1,3,4-oxadiazole

8436-0280 Screening compound: 2-(2,4-dimethoxyphenyl)-5-(methylsulfanyl)-1,3,4-oxadiazole
8436-0280 Screening compound: 2-(2,4-dimethoxyphenyl)-5-(methylsulfanyl)-1,3,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 8436-0280
2-(2,4-dimethoxyphenyl)-5-(methylsulfanyl)-1,3,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8436-0280

Molecular Formula

C11H12N2O3S (C11 H12 N2 O3 S)

Compound Name

2-(2,4-dimethoxyphenyl)-5-(methylsulfanyl)-1,3,4-oxadiazole

IUPAC name

2-(24-dimethoxyphenyl)-5-(methylsulfanyl)-134-oxadiazole

SMILES

COc(cc1)cc(OC)c1-c(o1)nnc1SC

InChI

InChI=1S/C11H12N2O3S/c1-14-7-4-5-8(9(6-7)15-2)10-12-13-11(16-10)17-3/h4-6H,1-3H3

InChI Key

SNKUCPGLOFLCTO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03122571

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

252.29

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.088

Distribution Coefficient, logD

2.088

Water Solubility, LogSw

-2.68

Polar Surface Area

45.510

Acid Dissociation Constant (pKa)

28.56

Base Dissociation Constant (pKb)

-1.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

8436-0280 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8436-0280 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8436-0280?
Check Price and Availability of 8436-0280, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8436-0280 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8436-0280
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8436-0280
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8436-0280 available by request