8442-0464 Screening compound: 2-[4-(2-hydroxyethyl)piperazin-1-yl]-7,7-dimethyl-5,6,7,8-tetrahydroquinazolin-5-one

8442-0464 Screening compound: 2-[4-(2-hydroxyethyl)piperazin-1-yl]-7,7-dimethyl-5,6,7,8-tetrahydroquinazolin-5-one
8442-0464 Screening compound: 2-[4-(2-hydroxyethyl)piperazin-1-yl]-7,7-dimethyl-5,6,7,8-tetrahydroquinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8442-0464
2-[4-(2-hydroxyethyl)piperazin-1-yl]-7,7-dimethyl-5,6,7,8-tetrahydroquinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8442-0464

Molecular Formula

C16H24N4O2 (C16 H24 N4 O2)

Compound Name

2-[4-(2-hydroxyethyl)piperazin-1-yl]-7,7-dimethyl-5,6,7,8-tetrahydroquinazolin-5-one

IUPAC name

2-[4-(2-hydroxyethyl)piperazin-1-yl]-77-dimethyl-5678-tetrahydroquinazolin-5-one

SMILES

CC(C)(Cc1c2cnc(N3CCN(CCO)CC3)n1)CC2=O

InChI

InChI=1S/C16H24N4O2/c1-16(2)9-13-12(14(22)10-16)11-17-15(18-13)20-5-3-19(4-6-20)7-8-21/h11,21H,3-10H2,1-2H3

InChI Key

LYOHAFNVQMFXRW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07469546

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

304.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.825

Distribution Coefficient, logD

0.663

Water Solubility, LogSw

-1.65

Polar Surface Area

56.826

Acid Dissociation Constant (pKa)

14.97

Base Dissociation Constant (pKb)

7.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

68.80

8442-0464 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 8442-0464 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8442-0464?
Check Price and Availability of 8442-0464, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8442-0464 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8442-0464
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8442-0464
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8442-0464 available by request