8539-0625 Screening compound: 9-chloro-2,4-bis(4-fluorophenyl)-5H-chromeno[4,3-b]pyridine

8539-0625 Screening compound: 9-chloro-2,4-bis(4-fluorophenyl)-5H-chromeno[4,3-b]pyridine
8539-0625 Screening compound: 9-chloro-2,4-bis(4-fluorophenyl)-5H-chromeno[4,3-b]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8539-0625
9-chloro-2,4-bis(4-fluorophenyl)-5H-chromeno[4,3-b]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8539-0625

Molecular Formula

C24H14ClF2NO (C24 H14 ClF2 NO)

Compound Name

9-chloro-2,4-bis(4-fluorophenyl)-5H-chromeno[4,3-b]pyridine

IUPAC name

9-chloro-24-bis(4-fluorophenyl)-5H-chromeno[43-b]pyridine

SMILES

Fc(cc1)ccc1-c1c(COc(cc2)c-3cc2Cl)c3nc(-c(cc2)ccc2F)c1

InChI

InChI=1S/C24H14ClF2NO/c25-16-5-10-23-20(11-16)24-21(13-29-23)19(14-1-6-17(26)7-2-14)12-22(28-24)15-3-8-18(27)9-4-15/h1-12H,13H2

InChI Key

VXNYHGUOPJIGEY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08278958

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.83

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

7.402

Distribution Coefficient, logD

7.397

Water Solubility, LogSw

-6.95

Polar Surface Area

17.271

Acid Dissociation Constant (pKa)

19.55

Base Dissociation Constant (pKb)

5.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.20

8539-0625 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8539-0625 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8539-0625?
Check Price and Availability of 8539-0625, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8539-0625 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8539-0625
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8539-0625
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8539-0625 available by request