8640-0608 Screening compound: N,N-diethyl-N'-[5-(2-furyl)-2,2-dimethyl-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]ethane-1,2-diamine

8640-0608 Screening compound: N,N-diethyl-N'-[5-(2-furyl)-2,2-dimethyl-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]ethane-1,2-diamine
8640-0608 Screening compound: N,N-diethyl-N'-[5-(2-furyl)-2,2-dimethyl-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]ethane-1,2-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8640-0608
N,N-diethyl-N'-[5-(2-furyl)-2,2-dimethyl-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]ethane-1,2-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8640-0608

Molecular Formula

C24H29N5O2S (C24 H29 N5 O2 S)

Compound Name

N,N-diethyl-N'-[5-(2-furyl)-2,2-dimethyl-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]ethane-1,2-diamine

IUPAC name

N-[2-(diethylamino)ethyl]-8-(furan-2-yl)-44-dimethyl-5-oxa-11-thia-91416-triazatetracyclo[8.7.0.0^{27}.0^{1217}]heptadeca-1(10)2(7)812(17)1315-hexaen-13-amine

SMILES

CCN(CC)CCNc1c2sc3nc(-c4ccco4)c(COC(C)(C)C4)c4c3c2ncn1

InChI

InChI=1S/C24H29N5O2S/c1-5-29(6-2)10-9-25-22-21-20(26-14-27-22)18-15-12-24(3,4)31-13-16(15)19(28-23(18)32-21)17-8-7-11-30-17/h7-8,11,14H,5-6,9-10,12-13H2,1-4H3,(H,25,26,27)

InChI Key

VLYYJYWNFSPRDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02241860

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.179

Distribution Coefficient, logD

3.186

Water Solubility, LogSw

-5.24

Polar Surface Area

61.348

Acid Dissociation Constant (pKa)

17.49

Base Dissociation Constant (pKb)

9.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

8640-0608 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

C-Met Library (15277 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 8640-0608 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8640-0608?
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What is the minimum amount of 8640-0608 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8640-0608
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8640-0608
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8640-0608 available by request