8640-0707 Screening compound: N,N-dibutyl-N-[5-isopropyl-2,2-dimethyl-10-(methylsulfanyl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]amine

8640-0707 Screening compound: N,N-dibutyl-N-[5-isopropyl-2,2-dimethyl-10-(methylsulfanyl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]amine
8640-0707 Screening compound: N,N-dibutyl-N-[5-isopropyl-2,2-dimethyl-10-(methylsulfanyl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8640-0707
N,N-dibutyl-N-[5-isopropyl-2,2-dimethyl-10-(methylsulfanyl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8640-0707

Molecular Formula

C26H38N4OS2 (C26 H38 N4 OS2)

Compound Name

N,N-dibutyl-N-[5-isopropyl-2,2-dimethyl-10-(methylsulfanyl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-yl]amine

IUPAC name

NN-dibutyl-44-dimethyl-15-(methylsulfanyl)-8-(propan-2-yl)-5-oxa-11-thia-91416-triazatetracyclo[8.7.0.0^{27}.0^{1217}]heptadeca-1(10)2(7)812(17)1315-hexaen-13-amine

SMILES

CCCCN(CCCC)c1c2sc3nc(C(C)C)c(COC(C)(C)C4)c4c3c2nc(SC)n1

InChI

InChI=1S/C26H38N4OS2/c1-8-10-12-30(13-11-9-2)23-22-21(28-25(29-23)32-7)19-17-14-26(5,6)31-15-18(17)20(16(3)4)27-24(19)33-22/h16H,8-15H2,1-7H3

InChI Key

GKDGHPAXKLQBDN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04029479

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.75

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

9.100

Distribution Coefficient, logD

9.099

Water Solubility, LogSw

-6.00

Polar Surface Area

39.302

Acid Dissociation Constant (pKa)

22.44

Base Dissociation Constant (pKb)

4.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

65.40

8640-0707 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8640-0707 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8640-0707?
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What is the minimum amount of 8640-0707 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8640-0707
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8640-0707
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8640-0707 available by request