A0000297 Screening compound: 5-(4-methoxyphenyl)-7-(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

A0000297 Screening compound: 5-(4-methoxyphenyl)-7-(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
A0000297 Screening compound: 5-(4-methoxyphenyl)-7-(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound A0000297
5-(4-methoxyphenyl)-7-(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

A0000297

Molecular Formula

C22H14F6N4O2 (C22 H14 F6 N4 O2)

Compound Name

5-(4-methoxyphenyl)-7-(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

5-(4-methoxyphenyl)-7-(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

COc(cc1)ccc1-c1nc2cc(C(Nc3cc(C(F)(F)F)ccc3)=O)nn2c(C(F)(F)F)c1

InChI

InChI=1S/C22H14F6N4O2/c1-34-15-7-5-12(6-8-15)16-10-18(22(26,27)28)32-19(30-16)11-17(31-32)20(33)29-14-4-2-3-13(9-14)21(23,24)25/h2-11H,1H3,(H,29,33)

InChI Key

NKFIHNMEAKSTIS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01194811

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.37

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.035

Distribution Coefficient, logD

6.033

Water Solubility, LogSw

-5.71

Polar Surface Area

49.032

Acid Dissociation Constant (pKa)

9.79

Base Dissociation Constant (pKb)

1.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

A0000297 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with A0000297 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound A0000297?
Check Price and Availability of A0000297, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of A0000297 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for A0000297
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for A0000297
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of A0000297 available by request