A0001343 Screening compound: 5-(2H-1,3-benzodioxol-5-yl)-N-(2,5-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

A0001343 Screening compound: 5-(2H-1,3-benzodioxol-5-yl)-N-(2,5-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
A0001343 Screening compound: 5-(2H-1,3-benzodioxol-5-yl)-N-(2,5-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound A0001343
5-(2H-1,3-benzodioxol-5-yl)-N-(2,5-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

A0001343

Molecular Formula

C23H17F3N4O5 (C23 H17 F3 N4 O5)

Compound Name

5-(2H-1,3-benzodioxol-5-yl)-N-(2,5-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

5-(2H-13-benzodioxol-5-yl)-N-(25-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

COc(cc1)cc(NC(c2nn3c(C(F)(F)F)cc(-c(cc4)cc5c4OCO5)nc3c2)=O)c1OC

InChI

InChI=1S/C23H17F3N4O5/c1-32-13-4-6-17(33-2)15(8-13)28-22(31)16-10-21-27-14(9-20(23(24,25)26)30(21)29-16)12-3-5-18-19(7-12)35-11-34-18/h3-10H,11H2,1-2H3,(H,28,31)

InChI Key

TYIOOJVWIILYIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02087719

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.41

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.690

Distribution Coefficient, logD

4.688

Water Solubility, LogSw

-4.46

Polar Surface Area

73.081

Acid Dissociation Constant (pKa)

9.77

Base Dissociation Constant (pKb)

2.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

A0001343 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
Targets:
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with A0001343 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound A0001343?
Check Price and Availability of A0001343, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of A0001343 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for A0001343
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for A0001343
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of A0001343 available by request