A0012882 Screening compound: 5-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

A0012882 Screening compound: 5-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
A0012882 Screening compound: 5-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound A0012882
5-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

A0012882

Molecular Formula

C23H19F3N4O4 (C23 H19 F3 N4 O4)

Compound Name

5-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

5-(34-dimethoxyphenyl)-N-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

COc(cc1)ccc1NC(c1nn2c(C(F)(F)F)cc(-c(cc3)cc(OC)c3OC)nc2c1)=O

InChI

InChI=1S/C23H19F3N4O4/c1-32-15-7-5-14(6-8-15)27-22(31)17-12-21-28-16(11-20(23(24,25)26)30(21)29-17)13-4-9-18(33-2)19(10-13)34-3/h4-12H,1-3H3,(H,27,31)

InChI Key

RUANWPPWAPOVCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02087863

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.492

Distribution Coefficient, logD

4.492

Water Solubility, LogSw

-4.44

Polar Surface Area

64.293

Acid Dissociation Constant (pKa)

11.88

Base Dissociation Constant (pKb)

2.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

A0012882 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with A0012882 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound A0012882?
Check Price and Availability of A0012882, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of A0012882 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for A0012882
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for A0012882
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of A0012882 available by request