A0012886 Screening compound: 5-(3,4-dimethoxyphenyl)-N-(2,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

A0012886 Screening compound: 5-(3,4-dimethoxyphenyl)-N-(2,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
A0012886 Screening compound: 5-(3,4-dimethoxyphenyl)-N-(2,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound A0012886
5-(3,4-dimethoxyphenyl)-N-(2,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

A0012886

Molecular Formula

C24H21F3N4O3 (C24 H21 F3 N4 O3)

Compound Name

5-(3,4-dimethoxyphenyl)-N-(2,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

5-(34-dimethoxyphenyl)-N-(24-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

Cc(cc1)cc(C)c1NC(c1nn2c(C(F)(F)F)cc(-c(cc3)cc(OC)c3OC)nc2c1)=O

InChI

InChI=1S/C24H21F3N4O3/c1-13-5-7-16(14(2)9-13)29-23(32)18-12-22-28-17(11-21(24(25,26)27)31(22)30-18)15-6-8-19(33-3)20(10-15)34-4/h5-12H,1-4H3,(H,29,32)

InChI Key

LMOQKLCFCNTYJK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02112180

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.191

Distribution Coefficient, logD

5.191

Water Solubility, LogSw

-5.02

Polar Surface Area

56.052

Acid Dissociation Constant (pKa)

11.84

Base Dissociation Constant (pKb)

2.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

A0012886 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with A0012886 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound A0012886?
Check Price and Availability of A0012886, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of A0012886 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for A0012886
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for A0012886
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of A0012886 available by request