A0019000 Screening compound: 6-(4-bromophenyl)-5-{[(4-chlorophenyl)methyl]sulfanyl}-3-(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

A0019000 Screening compound: 6-(4-bromophenyl)-5-{[(4-chlorophenyl)methyl]sulfanyl}-3-(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
A0019000 Screening compound: 6-(4-bromophenyl)-5-{[(4-chlorophenyl)methyl]sulfanyl}-3-(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound A0019000
6-(4-bromophenyl)-5-{[(4-chlorophenyl)methyl]sulfanyl}-3-(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

A0019000

Molecular Formula

C26H19BrClN3OS3 (C26 H19 BrClN3 OS3)

Compound Name

6-(4-bromophenyl)-5-{[(4-chlorophenyl)methyl]sulfanyl}-3-(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

6-(4-bromophenyl)-5-{[(4-chlorophenyl)methyl]sulfanyl}-3-(26-dimethylphenyl)-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

Cc1cccc(C)c1N(C(N=C(N(c(cc1)ccc1Br)C1=O)SCc(cc2)ccc2Cl)=C1S1)C1=S

InChI

InChI=1S/C26H19BrClN3OS3/c1-15-4-3-5-16(2)21(15)31-23-22(35-26(31)33)24(32)30(20-12-8-18(27)9-13-20)25(29-23)34-14-17-6-10-19(28)11-7-17/h3-13H,14H2,1-2H3

InChI Key

GSEWHYUXPDJZAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02649137

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

601.01

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.447

Distribution Coefficient, logD

7.447

Water Solubility, LogSw

-6.43

Polar Surface Area

26.353

Acid Dissociation Constant (pKa)

28.80

Base Dissociation Constant (pKb)

0.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

A0019000 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with A0019000 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound A0019000?
Check Price and Availability of A0019000, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of A0019000 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for A0019000
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for A0019000
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of A0019000 available by request