C072-0278 Screening compound: 2-[(4-fluorophenyl)thio]-N-(4-methoxybenzyl)quinoline-4-carboxamide

C072-0278 Screening compound: 2-[(4-fluorophenyl)thio]-N-(4-methoxybenzyl)quinoline-4-carboxamide
C072-0278 Screening compound: 2-[(4-fluorophenyl)thio]-N-(4-methoxybenzyl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C072-0278
2-[(4-fluorophenyl)thio]-N-(4-methoxybenzyl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C072-0278

Molecular Formula

C24H19FN2O2S (C24 H19 FN2 O2 S)

Compound Name

2-[(4-fluorophenyl)thio]-N-(4-methoxybenzyl)quinoline-4-carboxamide

IUPAC name

2-[(4-fluorophenyl)sulfanyl]-N-[(4-methoxyphenyl)methyl]quinoline-4-carboxamide

SMILES

COc1ccc(CNC(c2cc(Sc(cc3)ccc3F)nc3ccccc23)=O)cc1

InChI

InChI=1S/C24H19FN2O2S/c1-29-18-10-6-16(7-11-18)15-26-24(28)21-14-23(27-22-5-3-2-4-20(21)22)30-19-12-8-17(25)9-13-19/h2-14H,15H2,1H3,(H,26,28)

InChI Key

IQIBJUGDADOZQK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14716687

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.880

Distribution Coefficient, logD

5.880

Water Solubility, LogSw

-5.78

Polar Surface Area

39.616

Acid Dissociation Constant (pKa)

14.36

Base Dissociation Constant (pKb)

1.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

C072-0278 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system

References: we are preparing a list of scientific research reports with C072-0278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C072-0278?
Check Price and Availability of C072-0278, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C072-0278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C072-0278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C072-0278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C072-0278 available by request