C130-0284 Screening compound: 4-(2-methoxyphenyl)-N-[(thiophen-2-yl)methyl]-6-(trifluoromethyl)pyrimidin-2-amine

C130-0284 Screening compound: 4-(2-methoxyphenyl)-N-[(thiophen-2-yl)methyl]-6-(trifluoromethyl)pyrimidin-2-amine
C130-0284 Screening compound: 4-(2-methoxyphenyl)-N-[(thiophen-2-yl)methyl]-6-(trifluoromethyl)pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound C130-0284
4-(2-methoxyphenyl)-N-[(thiophen-2-yl)methyl]-6-(trifluoromethyl)pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C130-0284

Molecular Formula

C17H14F3N3OS (C17 H14 F3 N3 OS)

Compound Name

4-(2-methoxyphenyl)-N-[(thiophen-2-yl)methyl]-6-(trifluoromethyl)pyrimidin-2-amine

IUPAC name

4-(2-methoxyphenyl)-N-[(thiophen-2-yl)methyl]-6-(trifluoromethyl)pyrimidin-2-amine

SMILES

COc(cccc1)c1-c1cc(C(F)(F)F)nc(NCc2cccs2)n1

InChI

InChI=1S/C17H14F3N3OS/c1-24-14-7-3-2-6-12(14)13-9-15(17(18,19)20)23-16(22-13)21-10-11-5-4-8-25-11/h2-9H,10H2,1H3,(H,21,22,23)

InChI Key

MAKFKZOEVLBWIU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06164316

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.702

Distribution Coefficient, logD

4.702

Water Solubility, LogSw

-4.59

Polar Surface Area

38.556

Acid Dissociation Constant (pKa)

16.81

Base Dissociation Constant (pKb)

3.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

C130-0284 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

GABA Library (7115 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Ion Channels Focused Library (26372 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Eye
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C130-0284 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C130-0284?
Check Price and Availability of C130-0284, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C130-0284 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C130-0284
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C130-0284
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C130-0284 available by request