C141-0011 Screening compound: N-(3-chlorophenyl)-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

C141-0011 Screening compound: N-(3-chlorophenyl)-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
C141-0011 Screening compound: N-(3-chlorophenyl)-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C141-0011
N-(3-chlorophenyl)-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C141-0011

Molecular Formula

C25H23ClN2O4 (C25 H23 ClN2 O4)

Compound Name

N-(3-chlorophenyl)-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

IUPAC name

N-(3-chlorophenyl)-12-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

SMILES

COc1ccc(C(C(CC2=O)C(Nc3cccc(Cl)c3)=O)N2c(cc2)ccc2OC)cc1

InChI

InChI=1S/C25H23ClN2O4/c1-31-20-10-6-16(7-11-20)24-22(25(30)27-18-5-3-4-17(26)14-18)15-23(29)28(24)19-8-12-21(32-2)13-9-19/h3-14,22,24H,15H2,1-2H3,(H,27,30)

InChI Key

MOBIGOVXOJNRCJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14722210

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.92

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.688

Distribution Coefficient, logD

4.675

Water Solubility, LogSw

-5.03

Polar Surface Area

54.134

Acid Dissociation Constant (pKa)

8.91

Base Dissociation Constant (pKb)

-2.58

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

20.00

C141-0011 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C141-0011 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C141-0011?
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What is the minimum amount of C141-0011 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C141-0011
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C141-0011
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C141-0011 available by request