C141-0130 Screening compound: N-[2-(dipropylamino)ethyl]-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

C141-0130 Screening compound: N-[2-(dipropylamino)ethyl]-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
C141-0130 Screening compound: N-[2-(dipropylamino)ethyl]-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C141-0130
N-[2-(dipropylamino)ethyl]-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C141-0130

Molecular Formula

C27H37N3O4 (C27 H37 N3 O4)

Compound Name

N-[2-(dipropylamino)ethyl]-1,2-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

IUPAC name

N-[2-(dipropylamino)ethyl]-12-bis(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

SMILES

CCCN(CCC)CCNC(C(CC1=O)C(c(cc2)ccc2OC)N1c(cc1)ccc1OC)=O

InChI

InChI=1S/C27H37N3O4/c1-5-16-29(17-6-2)18-15-28-27(32)24-19-25(31)30(21-9-13-23(34-4)14-10-21)26(24)20-7-11-22(33-3)12-8-20/h7-14,24,26H,5-6,15-19H2,1-4H3,(H,28,32)

InChI Key

FJZROMHESKRYIG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14722260

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.61

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.637

Distribution Coefficient, logD

1.669

Water Solubility, LogSw

-3.66

Polar Surface Area

59.487

Acid Dissociation Constant (pKa)

11.29

Base Dissociation Constant (pKb)

9.36

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

48.10

C141-0130 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C141-0130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C141-0130?
Check Price and Availability of C141-0130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C141-0130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C141-0130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C141-0130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C141-0130 available by request