C154-0167 Screening compound: N-(2-chloro-4-fluorophenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

C154-0167 Screening compound: N-(2-chloro-4-fluorophenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
C154-0167 Screening compound: N-(2-chloro-4-fluorophenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C154-0167
N-(2-chloro-4-fluorophenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C154-0167

Molecular Formula

C19H16ClFN2O4 (C19 H16 ClFN2 O4)

Compound Name

N-(2-chloro-4-fluorophenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

IUPAC name

N-(2-chloro-4-fluorophenyl)-67-dimethoxy-2-methyl-1-oxo-12-dihydroisoquinoline-4-carboxamide

SMILES

CN(C=C(C(Nc(ccc(F)c1)c1Cl)=O)c(cc1OC)c2cc1OC)C2=O

InChI

InChI=1S/C19H16ClFN2O4/c1-23-9-13(18(24)22-15-5-4-10(21)6-14(15)20)11-7-16(26-2)17(27-3)8-12(11)19(23)25/h4-9H,1-3H3,(H,22,24)

InChI Key

JEJDNWORVBPPAI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14723221

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.8

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.830

Distribution Coefficient, logD

1.825

Water Solubility, LogSw

-3.58

Polar Surface Area

53.841

Acid Dissociation Constant (pKa)

6.44

Base Dissociation Constant (pKb)

-0.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

C154-0167 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C154-0167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C154-0167?
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What is the minimum amount of C154-0167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C154-0167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C154-0167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C154-0167 available by request