C154-0191 Screening compound: 4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-6,7-dimethoxy-2-methyl-1,2-dihydroisoquinolin-1-one

C154-0191 Screening compound: 4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-6,7-dimethoxy-2-methyl-1,2-dihydroisoquinolin-1-one
C154-0191 Screening compound: 4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-6,7-dimethoxy-2-methyl-1,2-dihydroisoquinolin-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound C154-0191
4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-6,7-dimethoxy-2-methyl-1,2-dihydroisoquinolin-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C154-0191

Molecular Formula

C23H24ClN3O4 (C23 H24 ClN3 O4)

Compound Name

4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-6,7-dimethoxy-2-methyl-1,2-dihydroisoquinolin-1-one

IUPAC name

4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-67-dimethoxy-2-methyl-12-dihydroisoquinolin-1-one

SMILES

CN(C=C(C(N(CC1)CCN1c1cccc(Cl)c1)=O)c(cc1OC)c2cc1OC)C2=O

InChI

InChI=1S/C23H24ClN3O4/c1-25-14-19(17-12-20(30-2)21(31-3)13-18(17)22(25)28)23(29)27-9-7-26(8-10-27)16-6-4-5-15(24)11-16/h4-6,11-14H,7-10H2,1-3H3

InChI Key

DUDHMIAOYQLMQJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14723236

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.91

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.628

Distribution Coefficient, logD

2.628

Water Solubility, LogSw

-3.34

Polar Surface Area

51.356

Acid Dissociation Constant (pKa)

28.31

Base Dissociation Constant (pKb)

2.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

C154-0191 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Human Kinases Annotated Library (2415 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with C154-0191 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C154-0191?
Check Price and Availability of C154-0191, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C154-0191 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C154-0191
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C154-0191
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C154-0191 available by request