C154-0224 Screening compound: N-(4-ethoxyphenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

C154-0224 Screening compound: N-(4-ethoxyphenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
C154-0224 Screening compound: N-(4-ethoxyphenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C154-0224
N-(4-ethoxyphenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C154-0224

Molecular Formula

C21H22N2O5 (C21 H22 N2 O5)

Compound Name

N-(4-ethoxyphenyl)-6,7-dimethoxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

IUPAC name

N-(4-ethoxyphenyl)-67-dimethoxy-2-methyl-1-oxo-12-dihydroisoquinoline-4-carboxamide

SMILES

CCOc(cc1)ccc1NC(C(c(cc1OC)c2cc1OC)=CN(C)C2=O)=O

InChI

InChI=1S/C21H22N2O5/c1-5-28-14-8-6-13(7-9-14)22-20(24)17-12-23(2)21(25)16-11-19(27-4)18(26-3)10-15(16)17/h6-12H,5H2,1-4H3,(H,22,24)

InChI Key

GIIXYTDWHFIXBI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14723253

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.568

Distribution Coefficient, logD

2.566

Water Solubility, LogSw

-3.16

Polar Surface Area

61.663

Acid Dissociation Constant (pKa)

9.80

Base Dissociation Constant (pKb)

0.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

C154-0224 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with C154-0224 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C154-0224?
Check Price and Availability of C154-0224, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C154-0224 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C154-0224
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C154-0224
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C154-0224 available by request