C167-0157 Screening compound: N-(3-fluoro-4-methylphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide

C167-0157 Screening compound: N-(3-fluoro-4-methylphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
C167-0157 Screening compound: N-(3-fluoro-4-methylphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C167-0157
N-(3-fluoro-4-methylphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C167-0157

Molecular Formula

C21H15FN2OS (C21 H15 FN2 OS)

Compound Name

N-(3-fluoro-4-methylphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide

IUPAC name

N-(3-fluoro-4-methylphenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide

SMILES

Cc(ccc(NC(c1cc(-c2cccs2)nc2ccccc12)=O)c1)c1F

InChI

InChI=1S/C21H15FN2OS/c1-13-8-9-14(11-17(13)22)23-21(25)16-12-19(20-7-4-10-26-20)24-18-6-3-2-5-15(16)18/h2-12H,1H3,(H,23,25)

InChI Key

RERGTTBVMXKGAJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14723546

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.849

Distribution Coefficient, logD

5.849

Water Solubility, LogSw

-5.73

Polar Surface Area

32.407

Acid Dissociation Constant (pKa)

10.89

Base Dissociation Constant (pKb)

1.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

C167-0157 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antiviral HBV Library (10007 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C167-0157 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C167-0157?
Check Price and Availability of C167-0157, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C167-0157 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C167-0157
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C167-0157
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C167-0157 available by request