C169-0378 Screening compound: 2-(3-{[3-(trifluoromethyl)phenyl]amino}imidazo[1,2-a]pyrazin-2-yl)phenol

C169-0378 Screening compound: 2-(3-{[3-(trifluoromethyl)phenyl]amino}imidazo[1,2-a]pyrazin-2-yl)phenol
C169-0378 Screening compound: 2-(3-{[3-(trifluoromethyl)phenyl]amino}imidazo[1,2-a]pyrazin-2-yl)phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C169-0378
2-(3-{[3-(trifluoromethyl)phenyl]amino}imidazo[1,2-a]pyrazin-2-yl)phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C169-0378

Molecular Formula

C19H13F3N4O (C19 H13 F3 N4 O)

Compound Name

2-(3-{[3-(trifluoromethyl)phenyl]amino}imidazo[1,2-a]pyrazin-2-yl)phenol

IUPAC name

2-(3-{[3-(trifluoromethyl)phenyl]amino}imidazo[12-a]pyrazin-2-yl)phenol

SMILES

Oc(cccc1)c1-c1c(Nc2cccc(C(F)(F)F)c2)n(ccnc2)c2n1

InChI

InChI=1S/C19H13F3N4O/c20-19(21,22)12-4-3-5-13(10-12)24-18-17(14-6-1-2-7-15(14)27)25-16-11-23-8-9-26(16)18/h1-11,24,27H

InChI Key

AWIXCAWRUKJRGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09694725

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.33

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.947

Distribution Coefficient, logD

4.936

Water Solubility, LogSw

-4.13

Polar Surface Area

43.745

Acid Dissociation Constant (pKa)

9.03

Base Dissociation Constant (pKb)

4.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

C169-0378 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antifungal Library (16415 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
Mechanism of action:
  • Epigenetic
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with C169-0378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C169-0378?
Check Price and Availability of C169-0378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C169-0378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C169-0378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C169-0378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C169-0378 available by request