C184-0423 Screening compound: 2-{[1-(2-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfonyl}-N-[2-(trifluoromethyl)phenyl]acetamide

C184-0423 Screening compound: 2-{[1-(2-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfonyl}-N-[2-(trifluoromethyl)phenyl]acetamide
C184-0423 Screening compound: 2-{[1-(2-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfonyl}-N-[2-(trifluoromethyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C184-0423
2-{[1-(2-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfonyl}-N-[2-(trifluoromethyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C184-0423

Molecular Formula

C26H22F3N3O4S (C26 H22 F3 N3 O4 S)

Compound Name

2-{[1-(2-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfonyl}-N-[2-(trifluoromethyl)phenyl]acetamide

IUPAC name

2-{[1-(2-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfonyl}-N-[2-(trifluoromethyl)phenyl]acetamide

SMILES

Cc(cc1)ccc1-c(nc1S(CC(Nc2c(C(F)(F)F)cccc2)=O)(=O)=O)cn1-c(cccc1)c1OC

InChI

InChI=1S/C26H22F3N3O4S/c1-17-11-13-18(14-12-17)21-15-32(22-9-5-6-10-23(22)36-2)25(31-21)37(34,35)16-24(33)30-20-8-4-3-7-19(20)26(27,28)29/h3-15H,16H2,1-2H3,(H,30,33)

InChI Key

FVPCYLNWDXEJDF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14724355

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

529.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.220

Distribution Coefficient, logD

5.220

Water Solubility, LogSw

-4.86

Polar Surface Area

70.896

Acid Dissociation Constant (pKa)

12.40

Base Dissociation Constant (pKb)

-1.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

C184-0423 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C184-0423 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C184-0423?
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What is the minimum amount of C184-0423 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C184-0423
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C184-0423
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C184-0423 available by request