C188-0454 Screening compound: 2-(4-chlorophenoxy)-N-[2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]-2-methylpropanamide

C188-0454 Screening compound: 2-(4-chlorophenoxy)-N-[2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]-2-methylpropanamide
C188-0454 Screening compound: 2-(4-chlorophenoxy)-N-[2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C188-0454
2-(4-chlorophenoxy)-N-[2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C188-0454

Molecular Formula

C24H21ClFN3O2 (C24 H21 ClFN3 O2)

Compound Name

2-(4-chlorophenoxy)-N-[2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]-2-methylpropanamide

IUPAC name

2-(4-chlorophenoxy)-N-[2-(4-fluorophenyl)-7-methylimidazo[12-a]pyridin-3-yl]-2-methylpropanamide

SMILES

CC(C)(C(Nc1c(-c(cc2)ccc2F)nc2n1ccc(C)c2)=O)Oc(cc1)ccc1Cl

InChI

InChI=1S/C24H21ClFN3O2/c1-15-12-13-29-20(14-15)27-21(16-4-8-18(26)9-5-16)22(29)28-23(30)24(2,3)31-19-10-6-17(25)7-11-19/h4-14H,1-3H3,(H,28,30)

InChI Key

LHGOYNUKJIOHSH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04460053

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.498

Distribution Coefficient, logD

5.498

Water Solubility, LogSw

-5.94

Polar Surface Area

38.077

Acid Dissociation Constant (pKa)

12.43

Base Dissociation Constant (pKb)

2.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

C188-0454 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C188-0454 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C188-0454?
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What is the minimum amount of C188-0454 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C188-0454
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C188-0454
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C188-0454 available by request