C200-8278 Screening compound: 6,7-dimethoxy-3-{5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione

C200-8278 Screening compound: 6,7-dimethoxy-3-{5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione
C200-8278 Screening compound: 6,7-dimethoxy-3-{5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound C200-8278
6,7-dimethoxy-3-{5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C200-8278

Molecular Formula

C26H32N4O5 (C26 H32 N4 O5)

Compound Name

6,7-dimethoxy-3-{5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione

IUPAC name

67-dimethoxy-3-{5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentyl}-1234-tetrahydroquinazoline-24-dione

SMILES

Cc1cccc(N(CC2)CCN2C(CCCCN(C(c(cc(c(OC)c2)OC)c2N2)=O)C2=O)=O)c1

InChI

InChI=1S/C26H32N4O5/c1-18-7-6-8-19(15-18)28-11-13-29(14-12-28)24(31)9-4-5-10-30-25(32)20-16-22(34-2)23(35-3)17-21(20)27-26(30)33/h6-8,15-17H,4-5,9-14H2,1-3H3,(H,27,33)

InChI Key

REMFTTUBIOBTJI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11999518

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.56

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.860

Distribution Coefficient, logD

2.844

Water Solubility, LogSw

-3.35

Polar Surface Area

75.372

Acid Dissociation Constant (pKa)

8.82

Base Dissociation Constant (pKb)

6.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

C200-8278 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C200-8278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C200-8278?
Check Price and Availability of C200-8278, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C200-8278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C200-8278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C200-8278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C200-8278 available by request