C224-1146 Screening compound: N-(3-chloro-2-methylphenyl)quinoline-8-sulfonamide

C224-1146 Screening compound: N-(3-chloro-2-methylphenyl)quinoline-8-sulfonamide
C224-1146 Screening compound: N-(3-chloro-2-methylphenyl)quinoline-8-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C224-1146
N-(3-chloro-2-methylphenyl)quinoline-8-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C224-1146

Molecular Formula

C16H13ClN2O2S (C16 H13 ClN2 O2 S)

Compound Name

N-(3-chloro-2-methylphenyl)quinoline-8-sulfonamide

IUPAC name

N-(3-chloro-2-methylphenyl)quinoline-8-sulfonamide

SMILES

Cc(c(NS(c1cccc2cccnc12)(=O)=O)ccc1)c1Cl

InChI

InChI=1S/C16H13ClN2O2S/c1-11-13(17)7-3-8-14(11)19-22(20,21)15-9-2-5-12-6-4-10-18-16(12)15/h2-10,19H,1H3

InChI Key

MPIZFXSOIUMWBG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00785364

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

332.81

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.564

Distribution Coefficient, logD

1.943

Water Solubility, LogSw

-3.66

Polar Surface Area

49.723

Acid Dissociation Constant (pKa)

5.79

Base Dissociation Constant (pKb)

0.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.30

C224-1146 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Aging Library (44940 compounds)

Cardiovascular Library (22201 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Nuclear receptors

References: we are preparing a list of scientific research reports with C224-1146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C224-1146?
Check Price and Availability of C224-1146, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C224-1146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C224-1146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C224-1146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C224-1146 available by request