C224-1757 Screening compound: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenyl-2-[(2-thienylsulfonyl)amino]acetamide

C224-1757 Screening compound: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenyl-2-[(2-thienylsulfonyl)amino]acetamide
C224-1757 Screening compound: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenyl-2-[(2-thienylsulfonyl)amino]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C224-1757
N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenyl-2-[(2-thienylsulfonyl)amino]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C224-1757

Molecular Formula

C19H14ClF3N2O3S2 (C19 H14 ClF3 N2 O3 S2)

Compound Name

N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenyl-2-[(2-thienylsulfonyl)amino]acetamide

IUPAC name

N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenyl-2-(thiophene-2-sulfonamido)acetamide

SMILES

O=C(C(c1ccccc1)NS(c1cccs1)(=O)=O)Nc(cc1)cc(C(F)(F)F)c1Cl

InChI

InChI=1S/C19H14ClF3N2O3S2/c20-15-9-8-13(11-14(15)19(21,22)23)24-18(26)17(12-5-2-1-3-6-12)25-30(27,28)16-7-4-10-29-16/h1-11,17,25H,(H,24,26)/t17-/m1/s1

InChI Key

OAXXQDCSGSIWDK-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD14732663

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.91

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.824

Distribution Coefficient, logD

4.532

Water Solubility, LogSw

-5.14

Polar Surface Area

65.672

Acid Dissociation Constant (pKa)

7.42

Base Dissociation Constant (pKb)

-1.84

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

10.53

C224-1757 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SH2 Library (10483 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C224-1757 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C224-1757?
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What is the minimum amount of C224-1757 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C224-1757
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C224-1757
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C224-1757 available by request