C259-0803 Screening compound: N-(2,5-difluorophenyl)-1-(thien-2-ylsulfonyl)piperidine-3-carboxamide

C259-0803 Screening compound: N-(2,5-difluorophenyl)-1-(thien-2-ylsulfonyl)piperidine-3-carboxamide
C259-0803 Screening compound: N-(2,5-difluorophenyl)-1-(thien-2-ylsulfonyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C259-0803
N-(2,5-difluorophenyl)-1-(thien-2-ylsulfonyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C259-0803

Molecular Formula

C16H16F2N2O3S2 (C16 H16 F2 N2 O3 S2)

Compound Name

N-(2,5-difluorophenyl)-1-(thien-2-ylsulfonyl)piperidine-3-carboxamide

IUPAC name

N-(25-difluorophenyl)-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1S(c1cccs1)(=O)=O)Nc(cc(cc1)F)c1F

InChI

InChI=1S/C16H16F2N2O3S2/c17-12-5-6-13(18)14(9-12)19-16(21)11-3-1-7-20(10-11)25(22,23)15-4-2-8-24-15/h2,4-6,8-9,11H,1,3,7,10H2,(H,19,21)/t11-/m0/s1

InChI Key

RTCALFBQGIPNQF-NSHDSACASA-N

MDL Number (MFCD)

MFCD14737127

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.735

Distribution Coefficient, logD

2.555

Water Solubility, LogSw

-3.26

Polar Surface Area

55.295

Acid Dissociation Constant (pKa)

7.69

Base Dissociation Constant (pKb)

-2.46

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.30

C259-0803 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C259-0803 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C259-0803?
Check Price and Availability of C259-0803, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C259-0803 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C259-0803
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C259-0803
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C259-0803 available by request