C259-1219 Screening compound: 1-[(5-bromo-1-propanoyl-2,3-dihydro-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(4-fluorophenyl)piperidine-3-carboxamide

C259-1219 Screening compound: 1-[(5-bromo-1-propanoyl-2,3-dihydro-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(4-fluorophenyl)piperidine-3-carboxamide
C259-1219 Screening compound: 1-[(5-bromo-1-propanoyl-2,3-dihydro-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(4-fluorophenyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C259-1219
1-[(5-bromo-1-propanoyl-2,3-dihydro-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(4-fluorophenyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C259-1219

Molecular Formula

C25H29BrFN3O4S (C25 H29 BrFN3 O4 S)

Compound Name

1-[(5-bromo-1-propanoyl-2,3-dihydro-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(4-fluorophenyl)piperidine-3-carboxamide

IUPAC name

1-[(5-bromo-1-propanoyl-23-dihydro-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(4-fluorophenyl)piperidine-3-carboxamide

SMILES

CCC(N(CCc1c2)c1cc(S(N(CCC1)CC1C(N(CC)c(cc1)ccc1F)=O)(=O)=O)c2Br)=O

InChI

InChI=1S/C25H29BrFN3O4S/c1-3-24(31)30-13-11-17-14-21(26)23(15-22(17)30)35(33,34)28-12-5-6-18(16-28)25(32)29(4-2)20-9-7-19(27)8-10-20/h7-10,14-15,18H,3-6,11-13,16H2,1-2H3/t18-/m0/s1

InChI Key

BXVZTYVXPQHRMZ-SFHVURJKSA-N

MDL Number (MFCD)

MFCD14737198

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

566.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.070

Distribution Coefficient, logD

4.070

Water Solubility, LogSw

-4.14

Polar Surface Area

62.653

Acid Dissociation Constant (pKa)

21.41

Base Dissociation Constant (pKb)

-1.39

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

C259-1219 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C259-1219 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C259-1219?
Check Price and Availability of C259-1219, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C259-1219 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C259-1219
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C259-1219
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C259-1219 available by request