C260-1580 Screening compound: N-(1-benzylpiperidin-4-yl)-4-[(1-{[(3-methylphenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]benzamide

C260-1580 Screening compound: N-(1-benzylpiperidin-4-yl)-4-[(1-{[(3-methylphenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]benzamide
C260-1580 Screening compound: N-(1-benzylpiperidin-4-yl)-4-[(1-{[(3-methylphenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C260-1580
N-(1-benzylpiperidin-4-yl)-4-[(1-{[(3-methylphenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C260-1580

Molecular Formula

C37H37N5O4 (C37 H37 N5 O4)

Compound Name

N-(1-benzylpiperidin-4-yl)-4-[(1-{[(3-methylphenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]benzamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-4-[(1-{[(3-methylphenyl)carbamoyl]methyl}-24-dioxo-1234-tetrahydroquinazolin-3-yl)methyl]benzamide

SMILES

Cc1cccc(NC(CN(c(cccc2)c2C(N2Cc(cc3)ccc3C(NC3CCN(Cc4ccccc4)CC3)=O)=O)C2=O)=O)c1

InChI

InChI=1S/C37H37N5O4/c1-26-8-7-11-31(22-26)38-34(43)25-41-33-13-6-5-12-32(33)36(45)42(37(41)46)24-28-14-16-29(17-15-28)35(44)39-30-18-20-40(21-19-30)23-27-9-3-2-4-10-27/h2-17,22,30H,18-21,23-25H2,1H3,(H,38,43)(H,39,44)

InChI Key

OAIXDALCNTTXIS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD26963701

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

615.73

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.813

Distribution Coefficient, logD

3.368

Water Solubility, LogSw

-4.51

Polar Surface Area

82.095

Acid Dissociation Constant (pKa)

13.03

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.30

C260-1580 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with C260-1580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C260-1580?
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What is the minimum amount of C260-1580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C260-1580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C260-1580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C260-1580 available by request