C260-2144 Screening compound: 2-[2,4-dioxo-3-(4-{2-oxo-2-[(tetrahydro-2-furanylmethyl)amino]ethyl}phenyl)-3,4-dihydro-1(2H)-quinazolinyl]-N-(2-methylphenyl)acetamide

C260-2144 Screening compound: 2-[2,4-dioxo-3-(4-{2-oxo-2-[(tetrahydro-2-furanylmethyl)amino]ethyl}phenyl)-3,4-dihydro-1(2H)-quinazolinyl]-N-(2-methylphenyl)acetamide
C260-2144 Screening compound: 2-[2,4-dioxo-3-(4-{2-oxo-2-[(tetrahydro-2-furanylmethyl)amino]ethyl}phenyl)-3,4-dihydro-1(2H)-quinazolinyl]-N-(2-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C260-2144
2-[2,4-dioxo-3-(4-{2-oxo-2-[(tetrahydro-2-furanylmethyl)amino]ethyl}phenyl)-3,4-dihydro-1(2H)-quinazolinyl]-N-(2-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C260-2144

Molecular Formula

C30H30N4O5 (C30 H30 N4 O5)

Compound Name

2-[2,4-dioxo-3-(4-{2-oxo-2-[(tetrahydro-2-furanylmethyl)amino]ethyl}phenyl)-3,4-dihydro-1(2H)-quinazolinyl]-N-(2-methylphenyl)acetamide

IUPAC name

2-[4-(1-{[(2-methylphenyl)carbamoyl]methyl}-24-dioxo-1234-tetrahydroquinazolin-3-yl)phenyl]-N-[(oxolan-2-yl)methyl]acetamide

SMILES

Cc(cccc1)c1NC(CN(c(cccc1)c1C(N1c2ccc(CC(NCC3OCCC3)=O)cc2)=O)C1=O)=O

InChI

InChI=1S/C30H30N4O5/c1-20-7-2-4-10-25(20)32-28(36)19-33-26-11-5-3-9-24(26)29(37)34(30(33)38)22-14-12-21(13-15-22)17-27(35)31-18-23-8-6-16-39-23/h2-5,7,9-15,23H,6,8,16-19H2,1H3,(H,31,35)(H,32,36)/t23-/m1/s1

InChI Key

PKLJIQBOLSFXCP-HSZRJFAPSA-N

MDL Number (MFCD)

MFCD14738411

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

526.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.535

Distribution Coefficient, logD

1.535

Water Solubility, LogSw

-2.59

Polar Surface Area

85.961

Acid Dissociation Constant (pKa)

12.70

Base Dissociation Constant (pKb)

1.14

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.67

C260-2144 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Dark Chemical Matter Library (18430 compounds)

Human Kinases Annotated Library (2415 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Pool

References: we are preparing a list of scientific research reports with C260-2144 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C260-2144?
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What is the minimum amount of C260-2144 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C260-2144
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C260-2144
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C260-2144 available by request