C265-0437 Screening compound: N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

C265-0437 Screening compound: N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide
C265-0437 Screening compound: N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C265-0437
N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C265-0437

Molecular Formula

C33H37FN4O4 (C33 H37 FN4 O4)

Compound Name

N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

IUPAC name

N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-1011-dimethoxy-5-oxo-7812b13-tetrahydro-5H-6-azatetraphene-13-carboxamide

SMILES

COc1cc(CCN(C2C(C(NCCCN(CC3)CCN3c(cc3)ccc3F)=O)c3c4cccc3)C4=O)c2cc1OC

InChI

InChI=1S/C33H37FN4O4/c1-41-28-20-22-12-15-38-31(27(22)21-29(28)42-2)30(25-6-3-4-7-26(25)33(38)40)32(39)35-13-5-14-36-16-18-37(19-17-36)24-10-8-23(34)9-11-24/h3-4,6-11,20-21,30-31H,5,12-19H2,1-2H3,(H,35,39)

InChI Key

KXORSRROTDPPFB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14739337

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

572.68

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.995

Distribution Coefficient, logD

2.409

Water Solubility, LogSw

-3.51

Polar Surface Area

62.705

Acid Dissociation Constant (pKa)

12.44

Base Dissociation Constant (pKb)

7.86

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

39.40

C265-0437 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
Agro:
  • Agro
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C265-0437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C265-0437?
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What is the minimum amount of C265-0437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C265-0437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C265-0437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C265-0437 available by request