C265-0457 Screening compound: N-[(2,5-dimethoxyphenyl)methyl]-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

C265-0457 Screening compound: N-[(2,5-dimethoxyphenyl)methyl]-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide
C265-0457 Screening compound: N-[(2,5-dimethoxyphenyl)methyl]-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C265-0457
N-[(2,5-dimethoxyphenyl)methyl]-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C265-0457

Molecular Formula

C29H30N2O6 (C29 H30 N2 O6)

Compound Name

N-[(2,5-dimethoxyphenyl)methyl]-10,11-dimethoxy-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

IUPAC name

N-[(25-dimethoxyphenyl)methyl]-1011-dimethoxy-5-oxo-7812b13-tetrahydro-5H-6-azatetraphene-13-carboxamide

SMILES

COc(cc1)cc(CNC(C(C2N3CCc(cc4OC)c2cc4OC)c(cccc2)c2C3=O)=O)c1OC

InChI

InChI=1S/C29H30N2O6/c1-34-19-9-10-23(35-2)18(13-19)16-30-28(32)26-20-7-5-6-8-21(20)29(33)31-12-11-17-14-24(36-3)25(37-4)15-22(17)27(26)31/h5-10,13-15,26-27H,11-12,16H2,1-4H3,(H,30,32)

InChI Key

LMKDWXSETCESOH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14739348

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

502.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.878

Distribution Coefficient, logD

2.878

Water Solubility, LogSw

-3.56

Polar Surface Area

70.794

Acid Dissociation Constant (pKa)

11.86

Base Dissociation Constant (pKb)

-1.89

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

31.00

C265-0457 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C265-0457 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C265-0457?
Check Price and Availability of C265-0457, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C265-0457 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C265-0457
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C265-0457
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C265-0457 available by request