C265-0468 Screening compound: 10,11-dimethoxy-N-[2-(3-methylphenyl)ethyl]-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

C265-0468 Screening compound: 10,11-dimethoxy-N-[2-(3-methylphenyl)ethyl]-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide
C265-0468 Screening compound: 10,11-dimethoxy-N-[2-(3-methylphenyl)ethyl]-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C265-0468
10,11-dimethoxy-N-[2-(3-methylphenyl)ethyl]-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C265-0468

Molecular Formula

C29H30N2O4 (C29 H30 N2 O4)

Compound Name

10,11-dimethoxy-N-[2-(3-methylphenyl)ethyl]-5-oxo-7,8,12b,13-tetrahydro-5H-6-azatetraphene-13-carboxamide

IUPAC name

1011-dimethoxy-N-[2-(3-methylphenyl)ethyl]-5-oxo-7812b13-tetrahydro-5H-6-azatetraphene-13-carboxamide

SMILES

Cc1cccc(CCNC(C(C2N3CCc(cc4OC)c2cc4OC)c(cccc2)c2C3=O)=O)c1

InChI

InChI=1S/C29H30N2O4/c1-18-7-6-8-19(15-18)11-13-30-28(32)26-21-9-4-5-10-22(21)29(33)31-14-12-20-16-24(34-2)25(35-3)17-23(20)27(26)31/h4-10,15-17,26-27H,11-14H2,1-3H3,(H,30,32)

InChI Key

VWGDVDLBUVESPO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14739351

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.443

Distribution Coefficient, logD

3.443

Water Solubility, LogSw

-3.72

Polar Surface Area

55.462

Acid Dissociation Constant (pKa)

12.18

Base Dissociation Constant (pKb)

-0.85

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

31.00

C265-0468 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with C265-0468 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C265-0468?
Check Price and Availability of C265-0468, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C265-0468 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C265-0468
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C265-0468
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C265-0468 available by request