C265-0575 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-(4-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}-1-oxo-1,2-dihydroisoquinolin-2-yl)acetamide

C265-0575 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-(4-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}-1-oxo-1,2-dihydroisoquinolin-2-yl)acetamide
C265-0575 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-(4-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}-1-oxo-1,2-dihydroisoquinolin-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C265-0575
N-(4-chloro-2-methoxy-5-methylphenyl)-2-(4-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}-1-oxo-1,2-dihydroisoquinolin-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C265-0575

Molecular Formula

C29H28ClFN4O5S (C29 H28 ClFN4 O5 S)

Compound Name

N-(4-chloro-2-methoxy-5-methylphenyl)-2-(4-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}-1-oxo-1,2-dihydroisoquinolin-2-yl)acetamide

IUPAC name

N-(4-chloro-2-methoxy-5-methylphenyl)-2-(4-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}-1-oxo-12-dihydroisoquinolin-2-yl)acetamide

SMILES

Cc(cc(c(OC)c1)NC(CN(C=C(c2c3cccc2)S(N(CC2)CCN2c(cccc2)c2F)(=O)=O)C3=O)=O)c1Cl

InChI

InChI=1S/C29H28ClFN4O5S/c1-19-15-24(26(40-2)16-22(19)30)32-28(36)18-34-17-27(20-7-3-4-8-21(20)29(34)37)41(38,39)35-13-11-33(12-14-35)25-10-6-5-9-23(25)31/h3-10,15-17H,11-14,18H2,1-2H3,(H,32,36)

InChI Key

OKEULEACVGGZEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14739411

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

599.08

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.327

Distribution Coefficient, logD

4.326

Water Solubility, LogSw

-4.58

Polar Surface Area

80.953

Acid Dissociation Constant (pKa)

9.88

Base Dissociation Constant (pKb)

1.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.10

C265-0575 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with C265-0575 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C265-0575?
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What is the minimum amount of C265-0575 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C265-0575
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C265-0575
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C265-0575 available by request