C273-0442 Screening compound: 4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

C273-0442 Screening compound: 4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol
C273-0442 Screening compound: 4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C273-0442
4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C273-0442

Molecular Formula

C22H18ClN3O4 (C22 H18 ClN3 O4)

Compound Name

4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

IUPAC name

4-{6-chloro-3-[(23-dihydro-14-benzodioxin-6-yl)amino]imidazo[12-a]pyridin-2-yl}-2-methoxyphenol

SMILES

COc(cc(cc1)-c2c(Nc(cc3)cc4c3OCCO4)n(cc(cc3)Cl)c3n2)c1O

InChI

InChI=1S/C22H18ClN3O4/c1-28-18-10-13(2-5-16(18)27)21-22(26-12-14(23)3-7-20(26)25-21)24-15-4-6-17-19(11-15)30-9-8-29-17/h2-7,10-12,24,27H,8-9H2,1H3

InChI Key

FORWZMHKVUGVDT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08682498

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.86

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.688

Distribution Coefficient, logD

3.616

Water Solubility, LogSw

-4.02

Polar Surface Area

57.574

Acid Dissociation Constant (pKa)

8.99

Base Dissociation Constant (pKb)

6.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

C273-0442 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Carbonic Anhydrase II Library (4939 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C273-0442 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C273-0442?
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What is the minimum amount of C273-0442 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C273-0442
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C273-0442
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C273-0442 available by request