C273-0446 Screening compound: 4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-6-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

C273-0446 Screening compound: 4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-6-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol
C273-0446 Screening compound: 4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-6-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C273-0446
4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-6-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C273-0446

Molecular Formula

C23H21N3O4 (C23 H21 N3 O4)

Compound Name

4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-6-methylimidazo[1,2-a]pyridin-2-yl}-2-methoxyphenol

IUPAC name

4-{3-[(23-dihydro-14-benzodioxin-6-yl)amino]-6-methylimidazo[12-a]pyridin-2-yl}-2-methoxyphenol

SMILES

Cc1cn2c(Nc(cc3)cc4c3OCCO4)c(-c(cc3)cc(OC)c3O)nc2cc1

InChI

InChI=1S/C23H21N3O4/c1-14-3-8-21-25-22(15-4-6-17(27)19(11-15)28-2)23(26(21)13-14)24-16-5-7-18-20(12-16)30-10-9-29-18/h3-8,11-13,24,27H,9-10H2,1-2H3

InChI Key

MONKOCZVNAKXRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08682469

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.371

Distribution Coefficient, logD

3.208

Water Solubility, LogSw

-3.11

Polar Surface Area

57.574

Acid Dissociation Constant (pKa)

8.99

Base Dissociation Constant (pKb)

7.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

C273-0446 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antimitotic Tubulin Library (17355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Carbonic Anhydrase II Library (4939 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C273-0446 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C273-0446?
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What is the minimum amount of C273-0446 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C273-0446
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C273-0446
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C273-0446 available by request