C274-0053 Screening compound: 2-(5-BROMOTHIOPHENE-2-SULFONAMIDO)-N-(4-CHLOROPHENYL)-2-PHENYLACETAMIDE

C274-0053 Screening compound: 2-(5-BROMOTHIOPHENE-2-SULFONAMIDO)-N-(4-CHLOROPHENYL)-2-PHENYLACETAMIDE
C274-0053 Screening compound: 2-(5-BROMOTHIOPHENE-2-SULFONAMIDO)-N-(4-CHLOROPHENYL)-2-PHENYLACETAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-0053
2-(5-BROMOTHIOPHENE-2-SULFONAMIDO)-N-(4-CHLOROPHENYL)-2-PHENYLACETAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-0053

Molecular Formula

C18H14BrClN2O3S2 (C18 H14 BrClN2 O3 S2)

Compound Name

2-(5-BROMOTHIOPHENE-2-SULFONAMIDO)-N-(4-CHLOROPHENYL)-2-PHENYLACETAMIDE

IUPAC name

n/a

SMILES

O=C(C(c1ccccc1)NS(c(s1)ccc1Br)(=O)=O)Nc(cc1)ccc1Cl

InChI

InChI=1S/C18H14BrClN2O3S2/c19-15-10-11-16(26-15)27(24,25)22-17(12-4-2-1-3-5-12)18(23)21-14-8-6-13(20)7-9-14/h1-11,17,22H,(H,21,23)/t17-/m1/s1

InChI Key

FRCQCCLDBUIYIH-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD14740094

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.81

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.734

Distribution Coefficient, logD

4.729

Water Solubility, LogSw

-5.08

Polar Surface Area

65.672

Acid Dissociation Constant (pKa)

9.39

Base Dissociation Constant (pKb)

-1.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

5.60

C274-0053 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SH2 Library (10483 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with C274-0053 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-0053?
Check Price and Availability of C274-0053, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C274-0053 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-0053
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-0053
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-0053 available by request