C274-0212 Screening compound: 2-(5-bromothiophene-2-sulfonamido)-2-phenyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide

C274-0212 Screening compound: 2-(5-bromothiophene-2-sulfonamido)-2-phenyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
C274-0212 Screening compound: 2-(5-bromothiophene-2-sulfonamido)-2-phenyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-0212
2-(5-bromothiophene-2-sulfonamido)-2-phenyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-0212

Molecular Formula

C20H20BrN3O5S3 (C20 H20 BrN3 O5 S3)

Compound Name

2-(5-bromothiophene-2-sulfonamido)-2-phenyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide

IUPAC name

2-(5-bromothiophene-2-sulfonamido)-2-phenyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide

SMILES

NS(c1ccc(CCNC(C(c2ccccc2)NS(c(s2)ccc2Br)(=O)=O)=O)cc1)(=O)=O

InChI

InChI=1S/C20H20BrN3O5S3/c21-17-10-11-18(30-17)32(28,29)24-19(15-4-2-1-3-5-15)20(25)23-13-12-14-6-8-16(9-7-14)31(22,26)27/h1-11,19,24H,12-13H2,(H,23,25)(H2,22,26,27)/t19-/m1/s1

InChI Key

UEYKFICUDQITNB-LJQANCHMSA-N

MDL Number (MFCD)

MFCD14740112

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

558.5

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.191

Distribution Coefficient, logD

2.185

Water Solubility, LogSw

-2.70

Polar Surface Area

117.439

Acid Dissociation Constant (pKa)

9.29

Base Dissociation Constant (pKb)

-0.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.00

C274-0212 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with C274-0212 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-0212?
Check Price and Availability of C274-0212, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C274-0212 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-0212
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-0212
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-0212 available by request